Tufted Angioma Treated with Low-dose Aspirin in a 1-year-old Filipino Boy

Tufted angioma (TA) is a rare, benign, vascular neoplasm of the skin. The diagnosis of this condition is infrequent due to its rare occurrence. Only 158 cases have been described as of 2015. The treatment reported in the literature is very limited with no clear guidelines on its management. Currently, there are no reported cases in the Philippines of TA treated with aspirin. This is a case of a 1-year-old Filipino boy presenting with multiple dusky red papules and plaques on the left side of the cheek, pre- and postauricular areas, parieto-occipital areas, chest, and upper back. His lesions started at 2 months of age, noted to increase in size, number, and thickness over time. Dermoscopy revealed homogenous erythematous background with perifollicular lacunae separated by thin septa. Histopathology revealed dilated vessels in the papillary dermis with proliferation of endothelial cells in lobules, surrounded by dilated crescent-shaped vascular channels in the dermis. The patient was treated with low-dose aspirin (5 mg/kg/day) once a day for 1 month with improvement. After 4 months from treatment, no new lesions, no increase in size, nor symptoms were noted. Low-dose aspirin is an effective and safe option for monotherapy of TA in pediatric patients.

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Publication Details

Journal
Journal of the Philippine Dermatological Society
Published
2025-05-01
DOI
https://doi.org/10.4103/jpds.jpds_37_24
Primary Topic
Vascular Malformations and Hemangiomas
Type
article
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article

Tufted Angioma Treated with Low-dose Aspirin in a 1-year-old Filipino Boy

M. Palmero, Dreena Cloi Lim Sy
Journal of the Philippine Dermatological Society
Vascular Malformations and Hemangiomas
article

Tufted Angioma Treated with Low-dose Aspirin in a 1-year-old Filipino Boy

M. Palmero, Dreena Cloi Lim Sy
article en

Abstract

Tufted angioma (TA) is a rare, benign, vascular neoplasm of the skin. The diagnosis of this condition is infrequent due to its rare occurrence. Only 158 cases have been described as of 2015. The treatment reported in the literature is very limited with no clear guidelines on its management. Currently, there are no reported cases in the Philippines of TA treated with aspirin. This is a case of a 1-year-old Filipino boy presenting with multiple dusky red papules and plaques on the left side of the cheek, pre- and postauricular areas, parieto-occipital areas, chest, and upper back. His lesions started at 2 months of age, noted to increase in size, number, and thickness over time. Dermoscopy revealed homogenous erythematous background with perifollicular lacunae separated by thin septa. Histopathology revealed dilated vessels in the papillary dermis with proliferation of endothelial cells in lobules, surrounded by dilated crescent-shaped vascular channels in the dermis. The patient was treated with low-dose aspirin (5 mg/kg/day) once a day for 1 month with improvement. After 4 months from treatment, no new lesions, no increase in size, nor symptoms were noted. Low-dose aspirin is an effective and safe option for monotherapy of TA in pediatric patients.

Journal of the Philippine Dermatological SocietyVol. 34(1)
University of Santo Tomas Hospital (PH)
Openalex Percentile: Top 75%
Vascular Malformations and Hemangiomas
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Tufted Angioma Treated with Low-dose Aspirin in a 1-year-old Filipino Boy — M. Palmero, Dreena Cloi Lim Sy · Journal of the Philippine Dermatological Society (2025) | TGRS Research Map | TGRS