A Newly Launched Nationwide Database Revealed Real-World Evidence on Systemic Therapy for Unresectable Hepatocellular Carcinoma in Japan: Hepatoma Registry of Integrating and Aggregating Electronic Health Record (HERITAGE)
Through establishing a comprehensive registry, this study unveiled evolving patterns in treatment regimens and shifts in patient demographics for systemic HCC therapy in Japan.
Authors
- Takamichi Murakami (ORCID: https://orcid.org/0000-0001-7782-548X)
- Ryosuke Tateishi (ORCID: https://orcid.org/0000-0003-3021-2517)
- Akiko Saito (ORCID: https://orcid.org/0000-0002-8977-4533)
- Hirohisa Yano (ORCID: https://orcid.org/0000-0003-4962-5784)
- Yoshinari Asaoka (ORCID: https://orcid.org/0000-0002-2805-8226)
- Kengo Yoshimitsu (ORCID: https://orcid.org/0000-0001-8530-2849)
- Norihiro Kokudo (ORCID: https://orcid.org/0000-0002-9003-8613)
- Masatoshi Kudo (ORCID: https://orcid.org/0000-0002-4102-3474)
- Naoya Kato (ORCID: https://orcid.org/0000-0001-5812-2818)
- Takumi Fukumoto (ORCID: https://orcid.org/0000-0003-1592-4524)
- Etsuro Hatano (ORCID: https://orcid.org/0000-0003-3407-1918)
- Kiyoshi Hasegawa (ORCID: https://orcid.org/0000-0001-8734-740X)
- Hiroko Iijima (ORCID: https://orcid.org/0000-0002-5841-8827)
- Mitsuo Shimada (ORCID: https://orcid.org/0000-0003-1255-4783)
- Yasuhide Yamada (ORCID: https://orcid.org/0000-0003-0692-8419)
- Masayuki Kurosaki (ORCID: https://orcid.org/0000-0001-7016-8931)
- Michiie Sakamoto (ORCID: https://orcid.org/0000-0003-3507-7369)
- Takashi Kokudo (ORCID: https://orcid.org/0000-0002-3729-1070)
- Hiroaki Miyata (ORCID: https://orcid.org/0000-0001-8800-6201)
- Yutaka Matsuyama (ORCID: https://orcid.org/0000-0003-2009-6831)
Institutions
- Chiba University (JP)
- Keio University (JP)
- Kyoto University (JP)
- The Football Association (GB)
- Fukuoka University (JP)
- National Center for Global Health and Medicine (JP)
- Fukui-ken Saiseikai Hospital (JP)
- Musashino Red Cross Hospital (JP)
- Kobe University (JP)
- The University of Tokyo (JP)
- International University of Health and Welfare (JP)
- Hyogo University (JP)
- Teikyo University (JP)
- Kindai University (JP)
- Tokushima University (JP)
Publication Details
- Journal
- Liver Cancer
- Published
- 2025-06-22
- DOI
- https://doi.org/10.1159/000546862
- Citations
- 5
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 4.68
Funders
- Eli Lilly and Company
- AstraZeneca
- Taiho Pharmaceutical
- National Center for Global Health and Medicine
- Ministry of Education, Culture, Sports, Science and Technology
- Ministry of Health, Labour and Welfare
- Eisai
- Otsuka Pharmaceutical
- Chugai Pharmaceutical
- Eli Lilly Japan
- Bayer Yakuhin