Predictors of the course of malignant ischemic stroke

INTRODUCTION. The most severe form of ischemic stroke is its malignant subtype, characterized by a high mortality rate. The cause of the severe course and unfavorable outcome of the disease, along with the volume of ischemia, is the addition of cerebral and extracerebral complications. AIM. To identify predictors of the course and outcome of malignant ischemic stroke (MCI). MATERIALS AND METHODS. Analysis of case histories is presented 55 patients with MCI in the MCA-supplied territory have been analysed. The study comprised patients aged from 44 to 92 years (average age: (71.4±1.6) years, Me = 73 years). Decompression hemicraniectomy was performed for 10 patients. RESULTS. Dislocation syndrome is an obligatory complication of MCI and the cause of death in most patients. The leading factors determining the course and outcome of the disease are cerebral, in particular, the volume of ischemic injury of the cerebral hemisphere and dislocation syndrome. CONCLUSION. MCI in the MCA-supplied territory is characterised by severe course resulting from the development of cerebral and extracerebral complications. The decisive events that determine the severe course and outcome of the disease are essentially a combination of multiple factors, which in turn necessitates an individual multidisciplinary approach to the choice of treatment tactics.