Shugan Decoction Ameliorated WAS‐Induced Abnormal Colonic Motility in Rats by Inhibiting Colonic <scp>TRPV4</scp> ‐ <scp> PGE <sub>2</sub> </scp> Signaling
SGD can ameliorate dysmotility of colonic longitudinal muscle and visceral hypersensitivity caused by WAS maybe by reducing the release of PGE<sub>2</sub> and decreasing the expression of TRPV4 and EP1.
Authors
- Youcheng He
- Shuyu Cai
- Lian Mo (ORCID: https://orcid.org/0000-0002-1875-2265)
- Yue Wu (ORCID: https://orcid.org/0000-0002-7349-959X)
- Ya Feng
- Jianye Yuan
- Chunyu Zhou (ORCID: https://orcid.org/0000-0002-6102-5629)
- Keyi Pan
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Neurogastroenterology & Motility
- Published
- 2025-06-22
- DOI
- https://doi.org/10.1111/nmo.70104
- Citations
- 1
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.81
Funders
- National Natural Science Foundation of China