Successful Methods for Switching from a Benzodiazepine Receptor Agonist to a Dual Orexin Receptor Antagonist for the Treatment of Insomnias
These findings suggest that in efforts to switch a patient's insomnia medication to a DORA, the tapering of ultra-short/short-acting BZRAs can lead to the successful switch to a DORA among patients under high-dose BZRA treatment, whereas careful switching is necessary for patients under long-term BZRA treatment.
Authors
- Atsushi Kimura (ORCID: https://orcid.org/0009-0009-2708-8763)
- Yasunori Oda (ORCID: https://orcid.org/0000-0002-4957-5847)
- Nobuhisa Kanahara (ORCID: https://orcid.org/0000-0001-8550-8003)
- Masaomi Iyo (ORCID: https://orcid.org/0000-0002-5384-857X)
- Masumi Tachibana (ORCID: https://orcid.org/0000-0003-1040-3957)
- Tadashi Hasegawa (ORCID: https://orcid.org/0000-0003-3134-6904)
Institutions
- Chiba University (JP)
- Chiba University Hospital (JP)
- Chiba Aoba Municipal Hospital (JP)
- Center for Forensic Mental Health, Chiba University (JP)
- International University of Health and Welfare (JP)
Publication Details
- Journal
- Clinical Psychopharmacology and Neuroscience
- Published
- 2025-06-22
- DOI
- https://doi.org/10.9758/cpn.25.1292
- Citations
- 1
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Chiba University