Reduced M3 muscarinic acetylcholine receptor expression in gestational diabetes mellitus: implications for placental dysfunction and vascular regulation
The findings suggest that reduced M3 mAChR expression in GDM placentas may contribute to impaired cholinergic signaling, vascular dysfunction, and placental insufficiency. These alterations may play a role in the adverse pregnancy outcomes associated with GDM.
Authors
- Fırat Aşir (ORCID: https://orcid.org/0000-0002-6384-9146)
- Ayşegül Aşır (ORCID: https://orcid.org/0000-0001-9056-144X)
- Elif Ağaçayak (ORCID: https://orcid.org/0000-0002-4215-1371)
- Emine Zeynep Yılmaz (ORCID: https://orcid.org/0000-0002-3537-8340)
- Süleyman Cemil Oğlak (ORCID: https://orcid.org/0000-0001-7634-3008)
- Tuğcan Korak (ORCID: https://orcid.org/0000-0003-4902-4022)
Institutions
- Dicle University (TR)
- Kocaeli Üniversitesi (TR)
Publication Details
- Journal
- The Journal of Maternal-Fetal & Neonatal Medicine
- Published
- 2025-06-22
- DOI
- https://doi.org/10.1080/14767058.2025.2521799
- Citations
- 3
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 6.17