Philadelphia Consensus on the Surgical Management of Xylazine-Associated Wounds in People Who Use Drugs
Xylazine-related wounds are increasingly presenting an addiction medicine and surgical dilemma in people who use drugs. Initially developed as a veterinary sedative, xylazine has been found increasingly added to illicitly manufactured fentanyl, reportedly to extend the duration of fentanyl intoxication. On the street, xylazine-laced fentanyl is known as “tranq,” “tranq dope,” and “zombie drug.” The management of xylazine-associated wounds needs multidisciplinary care. To better understand the scope of this new problem, review the best current evidence, and reach a consensus on best practices to manage xylazine-associated wounds, a formal consensus meeting was held, and the findings are presented here in this current concepts review.
Authors
- Sina Ramtin (ORCID: https://orcid.org/0000-0001-5197-6204)
- Lisa Rae
- Lara Carson Weinstein (ORCID: https://orcid.org/0000-0003-1862-3516)
- Katharine T. Criner-Woozley
- Asif M. Ilyas (ORCID: https://orcid.org/0000-0002-5636-9873)
- Erum N Ilyas (ORCID: https://orcid.org/0009-0009-7840-9731)
- Mark K. Solarz
- Jason D. Wink (ORCID: https://orcid.org/0000-0001-5603-6246)
- Rachel Haroz (ORCID: https://orcid.org/0000-0002-7217-1090)
- Andrew Miller (ORCID: https://orcid.org/0000-0001-6828-823X)
Institutions
- Thomas Jefferson University Hospital (US)
- Hospital of the University of Pennsylvania (US)
- Cooper University Hospital (US)
- Temple University Hospital (US)
- Rothman Institute (US)
- Drexel University (US)
Publication Details
- Journal
- SurgiColl
- Published
- 2025-06-22
- DOI
- https://doi.org/10.58616/001c.140602
- Citations
- 1
- Primary Topic
- Veterinary Pharmacology and Anesthesia
- Type
- article
- Field-Weighted Citation Impact
- 2.35