Impact of placental and peripheral blood DNA methylation on celiac disease susceptibility
Our results suggest that placenta does not seem to be a crucial effector in CeD, and show potentially causal relationships between blood DNAm and CeD, with independent signals in the HLA, and particularly in the HLA-DPA1 gene.
Authors
- Ariadna Cilleros‐Portet (ORCID: https://orcid.org/0000-0001-7564-6840)
- Carmen J. Marsit (ORCID: https://orcid.org/0000-0003-4566-150X)
- Sergi Marí (ORCID: https://orcid.org/0000-0003-2023-195X)
- Itziar González‐Moro (ORCID: https://orcid.org/0000-0002-6504-4931)
- Corina Lesseur (ORCID: https://orcid.org/0000-0001-6744-6750)
- Bárbara P. González‐García (ORCID: https://orcid.org/0000-0002-9287-6047)
- Nora Fernández‐Jiménez (ORCID: https://orcid.org/0000-0001-6307-0880)
- Iraia García‐Santisteban (ORCID: https://orcid.org/0000-0002-7912-385X)
- Alba Hernangomez‐Laderas (ORCID: https://orcid.org/0009-0001-9948-5399)
- José Ramón Bilbao (ORCID: https://orcid.org/0000-0002-3176-501X)
- Jia Chen (ORCID: https://orcid.org/0000-0002-1050-1832)
- Mikel de la Peña‐Sanz
Institutions
- Emory University (US)
- University of the Basque Country (ES)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Journal of Pediatric Gastroenterology and Nutrition
- Published
- 2025-06-22
- DOI
- https://doi.org/10.1002/jpn3.70124
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Euskal Herriko Unibertsitatea
- National Institutes of Health
- Instituto de Salud Carlos III
- Agencia Estatal de Investigación
- National Institute of Environmental Health Sciences
- European Social Fund