Predictive factors for post-therapeutic biochemical discordance in acromegaly: a monocentric analysis of 156 cases
Overall medication use is the strongest predictor of biochemical discrepancy, with irradiation potentially contributing. No clear distinguishing factors between biochemical discordance and persistent acromegaly were identified, except from disease recurrence. Managing patients with biochemical discrepancy similarly to those with persistent acromegaly may be advisable. Further research is needed to refine treatment strategies.
Authors
- Elena Tsourdi (ORCID: https://orcid.org/0000-0002-9582-1906)
- Stephan B. Sobottka
- Witold H. Polanski (ORCID: https://orcid.org/0000-0002-6603-5375)
- Tareq Adnan Juratli (ORCID: https://orcid.org/0000-0003-2236-6719)
- Ilker Y. Eyüpoglu (ORCID: https://orcid.org/0000-0002-8185-7764)
- Matthias Grüber
- Dimitrios Emmanouilidis
- Thomas Pinzer
Institutions
- University Hospital Carl Gustav Carus (DE)
- Technische Universität Dresden (DE)
Publication Details
- Journal
- Pituitary
- Published
- 2025-06-22
- DOI
- https://doi.org/10.1007/s11102-025-01547-8
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Technische Universität Dresden