A Multi-Stage Genomic Approach to Uncover Druggable Gene Targets and Neural Pathways in Postpartum Depression

Our analysis identified CLCN7 as a potential causal factor in PPD, with its effect mediated through brain connectivity. These findings offer targets for future studies and therapeutic strategies for PPD.

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Publication Details

Journal
Archives of Medical Science
Published
2025-06-22
DOI
https://doi.org/10.5114/aoms/206043
Citations
1
Primary Topic
Maternal Mental Health During Pregnancy and Postpartum
Type
article
Field-Weighted Citation Impact
1.88
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article

A Multi-Stage Genomic Approach to Uncover Druggable Gene Targets and Neural Pathways in Postpartum Depression

Huirong Hu, Chui-Yu Li, Zhi-Yuan Chen, Hai-Ping You et al.
1 citations
Archives of Medical Science
Maternal Mental Health During Pregnancy and Postpartum
1.88
article

A Multi-Stage Genomic Approach to Uncover Druggable Gene Targets and Neural Pathways in Postpartum Depression

Huirong Hu, Chui-Yu Li, Zhi-Yuan Chen, Hai-Ping You, Wen-Xi Xie
article en
1 citations

Abstract

Our analysis identified CLCN7 as a potential causal factor in PPD, with its effect mediated through brain connectivity. These findings offer targets for future studies and therapeutic strategies for PPD.

Archives of Medical ScienceVol. 21(5)
Fujian Medical University (CN), Second Affiliated Hospital of Fujian Medical University (CN)
Good health and well-being
Openalex Percentile: Top 15%
Maternal Mental Health During Pregnancy and Postpartum
1.88
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