Establishment and Characterization of a Durable and Versatile Endometrial Cancer Organoid Database
Abstract Objective To construct standardized endometrial cancer organoids. Method Preparation and culture of endometrial carcinoma organoids from human endometrial carcinoma tissues. Verified the consistency between organoids and primary carcinoma tissues through microscopic cell appearance and immunohistochemistry. Result The appearance and biomarkers of the constructed endometrial carcinoma organoid were consistent with those endometrial carcinoma cells from patients. Conclusion The appearance and biomarkers of the endometrial carcinoma organoid were consistent with those endometrial carcinoma cells from patients.
Authors
- Xuefeng Jiang (ORCID: https://orcid.org/0000-0002-3545-5166)
- Gangwei Wang (ORCID: https://orcid.org/0000-0002-5005-5099)
- Xingping Xu
- Jianwei Chen (ORCID: https://orcid.org/0000-0003-0033-2147)
- Yu Zhang (ORCID: https://orcid.org/0000-0001-5274-9783)
- Yifen Li (ORCID: https://orcid.org/0000-0003-3279-6712)
Institutions
- Sun Yat-sen University (CN)
- Tsinghua–Berkeley Shenzhen Institute (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- Indian Journal of Gynecologic Oncology
- Published
- 2025-06-22
- DOI
- https://doi.org/10.1007/s40944-025-01006-z
- Citations
- 1
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Tsinghua-Berkeley Shenzhen institute