Isoginkgetin protects chondrocytes and inhibits osteoarthritis through NF-κB and P21 signaling pathway
IGK protects articular cartilage and reduces the progression of OA in a mouse model and shows promise as a potential therapeutic strategy for OA.
Authors
- Xi Chen (ORCID: https://orcid.org/0009-0003-6156-4811)
- Shasha Du (ORCID: https://orcid.org/0000-0002-2650-7286)
- Huanhuan Xu (ORCID: https://orcid.org/0000-0002-0376-0035)
- Changyu Liu (ORCID: https://orcid.org/0000-0003-2717-3684)
- Mingli Xu (ORCID: https://orcid.org/0000-0003-1079-461X)
Institutions
- Wuhan No.1 Hospital (CN)
- Wuhan Children's Hospital (CN)
- Wuhan No.9 Hospital (CN)
- Daye People's Hospital (CN)
- Tongji Hospital (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2025-06-22
- DOI
- https://doi.org/10.1186/s10020-025-01302-6
- Citations
- 4
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 6.67
Funders
- Department of Science and Technology, Hubei Provincial People's Government