Multimerin-1 modulates macrophage M2 polarization and enhances tumor cell stemness in glioblastoma

MMRN1 is a critical BTSC-related biomarker that contributes to GBM progression by enhancing tumor stemness and modulating the immune microenvironment. Targeting MMRN1 May represent a promising therapeutic approach for GBM treatment.

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Publication Details

Journal
Neurological Research
Published
2025-06-21
DOI
https://doi.org/10.1080/01616412.2025.2520060
Primary Topic
Immune cells in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Multimerin-1 modulates macrophage M2 polarization and enhances tumor cell stemness in glioblastoma

Wuqiao Bao, Chao Huang, Yong-Zhi Zhou, Xiaobing Zhang et al.
Neurological Research
Immune cells in cancer
article

Multimerin-1 modulates macrophage M2 polarization and enhances tumor cell stemness in glioblastoma

Wuqiao Bao, Chao Huang, Yong-Zhi Zhou, Xiaobing Zhang, Chang‐Ming Dong, Xuebin Yu
article en

Abstract

MMRN1 is a critical BTSC-related biomarker that contributes to GBM progression by enhancing tumor stemness and modulating the immune microenvironment. Targeting MMRN1 May represent a promising therapeutic approach for GBM treatment.

Neurological ResearchVol. 48(1)
Shaoxing People's Hospital (CN)
Zero hunger
Openalex Percentile: Top 84%
Immune cells in cancer
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