Prevalence and clinical relavance of germline mutations in Chinese patients with pancreatic cancer
In this cohort, 5.2% of PC patients possessed therapeutically relevant P/LPGVs. Germline testing may provide prognostic benefits and is crucial for therapy selection, particularly in metastatic PC patients.
Authors
- Yijin Gu
- Jiejie Qin
- Hao Chen
- Dan Li (ORCID: https://orcid.org/0000-0002-8841-8991)
- Jun Zhang (ORCID: https://orcid.org/0000-0002-9709-8854)
- Yu Jiang (ORCID: https://orcid.org/0000-0001-5058-3484)
- Yang Liu (ORCID: https://orcid.org/0000-0003-1556-5170)
- Baiyong Shen (ORCID: https://orcid.org/0009-0004-7447-9541)
- Jiabin Jin
Institutions
- Ruijin Hospital (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-06-21
- DOI
- https://doi.org/10.1186/s12964-025-02281-1
- Citations
- 1
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.05