Acute cardiotoxicity in pediatric and adolescent patients with solid tumors treated with tyrosine kinase inhibitors
Despite changes in cardiac function while on MTKIs, reductions because of cardiac toxicity were infrequent. Routine monitoring of cardiac function during MTKI use and early intervention may enable patients to continue therapy while safeguarding cardiovascular health.
Authors
- Jessica Gartrell (ORCID: https://orcid.org/0000-0002-1722-2924)
- Daniel A. Mulrooney (ORCID: https://orcid.org/0000-0003-2351-9115)
- Patricia Pease
- Gary Beasley (ORCID: https://orcid.org/0000-0001-6137-6114)
- Michael W. Bishop (ORCID: https://orcid.org/0000-0003-3926-1446)
- Sara Michele Federico (ORCID: https://orcid.org/0000-0002-5807-4876)
- Alberto S. Pappo (ORCID: https://orcid.org/0000-0002-5338-3979)
- Haitao Pan (ORCID: https://orcid.org/0000-0003-4457-7349)
- Chia‐Wei Hsu (ORCID: https://orcid.org/0000-0002-0493-9870)
- C. Meredith
- Sara Helmig (ORCID: https://orcid.org/0000-0002-7059-5869)
- Anthony M. Christensen (ORCID: https://orcid.org/0009-0008-7232-9493)
Institutions
- Arkansas Children's Hospital (US)
- St. Jude Children's Research Hospital (US)
- University of Iowa Stead Family Children’s Hospital (US)
Publication Details
- Journal
- Cancer
- Published
- 2025-06-21
- DOI
- https://doi.org/10.1002/cncr.35940
- Citations
- 1
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- St. Jude Children's Research Hospital
- American Lebanese Syrian Associated Charities