Pharmacokinetic Comparison of Novel Tablet-in-Tablet and Conventional Ketorolac Tromethamine Tablets in Beagle Dogs
The results of this study suggest that the development of a novel KT tablet formulation utilizing the push-pull osmotic pump (PPOP) and tablet-in-tablet techniques warrants further investigation in clinical trials.
Authors
- Yuan Zeng (ORCID: https://orcid.org/0000-0002-3270-2459)
- Wen‐Hsin Lin (ORCID: https://orcid.org/0000-0002-7216-1626)
- Xiangyang Xie (ORCID: https://orcid.org/0000-0001-8260-3988)
- Guowei Zhang (ORCID: https://orcid.org/0000-0001-7639-5860)
- Yuliang Li (ORCID: https://orcid.org/0000-0001-5279-0399)
- Zhilong Chen (ORCID: https://orcid.org/0000-0001-9716-8368)
- Yihui Ma (ORCID: https://orcid.org/0000-0003-2870-2402)
- Hui Liu
Institutions
- Wuhan Third Hospital (CN)
- Central Hospital of Wuhan (CN)
- Wuhan General Hospital of Guangzhou (CN)
- Wuhan University of Science and Technology (CN)
Publication Details
- Journal
- Drugs in R&D
- Published
- 2025-06-21
- DOI
- https://doi.org/10.1007/s40268-025-00516-7
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.00