An immunoinformatics approach in designing high-coverage mRNA multi-epitope vaccine against multivariant SARS-CoV-2
As a result, an mRNA vaccine candidate was obtained with high population coverage and could induce a robust and protective immune response against multiple variants of SARS-CoV-2. Therefore, further studies are required to validate the safety and efficacy of the proposed vaccine candidate.
Authors
- Husna Nugrahapraja (ORCID: https://orcid.org/0000-0002-7637-272X)
- Ernawati Arifin Giri-Rachman (ORCID: https://orcid.org/0009-0009-2325-5763)
- Catur Riani (ORCID: https://orcid.org/0000-0001-7082-0264)
- Marselina Irasonia Tan (ORCID: https://orcid.org/0000-0001-9938-8663)
- Anita Artarini (ORCID: https://orcid.org/0000-0002-0235-7973)
- Reza Aditama (ORCID: https://orcid.org/0009-0006-1797-1059)
- Rizarullah Rizarullah
- Dessy Natalia (ORCID: https://orcid.org/0000-0001-8228-1149)
- Al Mirahma Febri Kurnianti
- Aditya Hanung Setyadi
Institutions
- Bandung Institute of Technology (ID)
Publication Details
- Journal
- Journal of Genetic Engineering and Biotechnology
- Published
- 2025-06-21
- DOI
- https://doi.org/10.1016/j.jgeb.2025.100524
- Citations
- 6
- Primary Topic
- vaccines and immunoinformatics approaches
- Type
- article
- Field-Weighted Citation Impact
- 4.84
Funders
- Badan Riset dan Inovasi Nasional