Mediating role of inflammatory markers (NLR, PLR, SII, SIRI) in the association between 25(OH)D deficiency and obesity in children and adolescents
This study demonstrates a significant association between 25(OH)D deficiency and obesity in children and adolescents, with inflammatory markers-particularly NLR and SII-playing a partial mediating role in this relationship. These findings indicate that 25(OH)D may influence the development of obesity by modulating the inflammatory response.
Authors
- Xiaoshan M. Shao (ORCID: https://orcid.org/0000-0003-3190-2288)
- Y. Li (ORCID: https://orcid.org/0000-0001-8344-1722)
Institutions
- The First People's Hospital of Guiyang (CN)
- Guizhou Provincial People's Hospital (CN)
Publication Details
- Journal
- Journal of Health Population and Nutrition
- Published
- 2025-06-21
- DOI
- https://doi.org/10.1186/s41043-025-00981-5
- Citations
- 8
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 11.77