The Utility of Copeptin Measurement in Hospitalized Pediatric Patients with SIADH

Copeptin levels correlated with a clinical diagnosis of SIADH in hospitalized pediatric patients, particularly if elevated above 8.0 pmol/L at the time of hyponatremia, and the patient met the Schwartz and Bartter clinical criteria for SIADH. However, in some cases of SIADH, copeptin levels may be in normal range and could be considered inappropriately high for the degree of hyponatremia.