Atypical tinea corporis with Id reaction: A case report and successful treatment with upadacitinib

Atypical tinea corporis, characterized by clinical manifestations that resemble other skin disorders, can lead to misdiagnosis and delayed treatment. This 67-year-old male had a seven-month history of pruritic skin lesions resembling subcorneal pustular dermatosis. Dermatological exam and fungal culture confirmed <i>Trichophyton rubrum</i>-induced atypical tinea corporis. After oral itraconazole treatment, he developed symmetrical eczematous lesions (Id reaction) on his extremities. Initial treatment was ineffective, so upadacitinib was administered, resulting in significant improvement at eight weeks. This case highlights atypical tinea presentations, Id reactions, and introduces upadacitinib as a novel treatment option for refractory Id reactions.

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Publication Details

Journal
IDCases
Published
2025-01-01
DOI
https://doi.org/10.1016/j.idcr.2025.e02300
Citations
1
Primary Topic
Nail Diseases and Treatments
Type
article
Field-Weighted Citation Impact
1.35
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article

Atypical tinea corporis with Id reaction: A case report and successful treatment with upadacitinib

Zhixun Xiao, Xinhong Su, Jing Mao, Chao Ji et al.
1 citations
IDCases
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article

Atypical tinea corporis with Id reaction: A case report and successful treatment with upadacitinib

Zhixun Xiao, Xinhong Su, Jing Mao, Chao Ji, Ying Chen, Ting Gong, Zheyu Zhuang, Siyi Bao, Zequn Tong
article en
1 citations

Abstract

Atypical tinea corporis, characterized by clinical manifestations that resemble other skin disorders, can lead to misdiagnosis and delayed treatment. This 67-year-old male had a seven-month history of pruritic skin lesions resembling subcorneal pustular dermatosis. Dermatological exam and fungal culture confirmed <i>Trichophyton rubrum</i>-induced atypical tinea corporis. After oral itraconazole treatment, he developed symmetrical eczematous lesions (Id reaction) on his extremities. Initial treatment was ineffective, so upadacitinib was administered, resulting in significant improvement at eight weeks. This case highlights atypical tinea presentations, Id reactions, and introduces upadacitinib as a novel treatment option for refractory Id reactions.

IDCasesVol. 41
North Sichuan Medical University (CN), Fujian Medical University (CN), Shanghai Jiao Tong University (CN), Shanghai Children's Medical Center (CN), Affiliated Hospital of North Sichuan Medical College (CN), First Affiliated Hospital of Fujian Medical University (CN)
Openalex Percentile: Top 18%
Nail Diseases and Treatments
1.35
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