Second malignancies in patients with deficient mismatch repair system/microsatellite instability-high colorectal cancer

It seems important to follow patients with a history of dMMR/MSI-H CRC due to the high risk of second tumors, even in sporadic cases. Second cancers in patients with sporadic dMMR/MSI-H CRC are rarely associated with a dMMR/MSI-H phenotype.

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Publication Details

Journal
Therapeutic Advances in Gastroenterology
Published
2025-06-21
DOI
https://doi.org/10.1177/17562848251347375
Citations
1
Primary Topic
Genetic factors in colorectal cancer
Type
article
Field-Weighted Citation Impact
1.47
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Second malignancies in patients with deficient mismatch repair system/microsatellite instability-high colorectal cancer

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Second malignancies in patients with deficient mismatch repair system/microsatellite instability-high colorectal cancer

Valérie Moulin, Marie‐Luce Auriault, Julie Godet, Arnaud Chong‐Si‐Tsaon, David Tougeron, Camille Evrard, Paul Franques, Gaëlle Tachon, Audelaure Junca, Lucie Lebeau, É. Frouin, Lucie Karayan‐Tapon, Pierre Moreau, Robier A. Aguillon
article en
1 citations

Abstract

It seems important to follow patients with a history of dMMR/MSI-H CRC due to the high risk of second tumors, even in sporadic cases. Second cancers in patients with sporadic dMMR/MSI-H CRC are rarely associated with a dMMR/MSI-H phenotype.

Therapeutic Advances in GastroenterologyVol. 18
Université de Poitiers (FR), Centre Hospitalier de La Rochelle (FR)
Good health and well-being
Openalex Percentile: Top 18%
Genetic factors in colorectal cancer
1.47
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