Evaluating the therapeutic efficacy of a Benzofuran-Enaminone derivative for the management of Alzheimer’s disease (AD)-like pathology in rats through regulating the expression of apoptosis and AD-related genes
This study could be regarded as an initial step in drug discovery for testing this new chemical entity as a potent anti-AD therapeutic agent.
Authors
- Hanan F. Aly (ORCID: https://orcid.org/0000-0003-3642-1571)
- Ghadha Ibrahim Fouad (ORCID: https://orcid.org/0000-0003-3665-3153)
- Somaia S. Abd El‐Karim (ORCID: https://orcid.org/0000-0002-3463-3047)
- Nahla N. Kamel (ORCID: https://orcid.org/0000-0002-9037-5038)
- Mohamed B. Shalaby (ORCID: https://orcid.org/0000-0002-3006-393X)
- Dalia A. Taha (ORCID: https://orcid.org/0000-0002-2234-2250)
- Kawkab A. Ahmed (ORCID: https://orcid.org/0000-0001-7376-7411)
- Nagy S. El-Rigal (ORCID: https://orcid.org/0000-0002-4231-0926)
- Wagdy K. B. Khalil (ORCID: https://orcid.org/0000-0002-0598-7217)
- Maha Z. Rizk (ORCID: https://orcid.org/0000-0002-1289-3112)
- Doha H. Abou Baker (ORCID: https://orcid.org/0000-0001-6853-041X)
Institutions
- Cairo University (EG)
- National Research Centre (EG)
- General Organization For Teaching Hospitals and Institutes (EG)
- Ministry of Health and Population (EG)
Publication Details
- Journal
- Neurological Research
- Published
- 2025-06-21
- DOI
- https://doi.org/10.1080/01616412.2025.2520021
- Citations
- 2
- Primary Topic
- Cholinesterase and Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.79