Can generative AI reliably synthesise literature? exploring hallucination issues in ChatGPT

Abstract This study evaluates the capabilities and limitations of generative AI, specifically ChatGPT, in conducting systematic literature reviews. Using the PRISMA methodology, we analysed 124 recent studies, focusing in-depth on a subset of 40 selected through strict inclusion criteria. Findings show that ChatGPT can enhance efficiency, with reported workload reductions averaging around 60–65%, though accuracy varies widely by task and context. In structured domains such as clinical research, title and abstract screening sensitivity ranged from 80.6% to 96.2%, while precision dropped as low as 4.6% in more interpretive tasks. Hallucination rates reached 91%, underscoring the need for careful oversight. Comparative analysis shows that AI matches or exceeds human performance in simple screening but underperforms in nuanced synthesis. To support more reliable integration, we introduce the Systematic Research Processing Framework (SRPF) as a guiding model for hybrid AI–human collaboration in research review workflows.

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Publication Details

Journal
AI & Society
Published
2025-06-21
DOI
https://doi.org/10.1007/s00146-025-02406-7
Citations
19
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
12.43
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article

Can generative AI reliably synthesise literature? exploring hallucination issues in ChatGPT

Noor Haitham Saleem, Amr Adel
19 citations
AI & Society
Artificial Intelligence in Healthcare and Education
12.43
article

Can generative AI reliably synthesise literature? exploring hallucination issues in ChatGPT

Noor Haitham Saleem, Amr Adel
article en
19 citations

Abstract

Abstract This study evaluates the capabilities and limitations of generative AI, specifically ChatGPT, in conducting systematic literature reviews. Using the PRISMA methodology, we analysed 124 recent studies, focusing in-depth on a subset of 40 selected through strict inclusion criteria. Findings show that ChatGPT can enhance efficiency, with reported workload reductions averaging around 60–65%, though accuracy varies widely by task and context. In structured domains such as clinical research, title and abstract screening sensitivity ranged from 80.6% to 96.2%, while precision dropped as low as 4.6% in more interpretive tasks. Hallucination rates reached 91%, underscoring the need for careful oversight. Comparative analysis shows that AI matches or exceeds human performance in simple screening but underperforms in nuanced synthesis. To support more reliable integration, we introduce the Systematic Research Processing Framework (SRPF) as a guiding model for hybrid AI–human collaboration in research review workflows.

AI & SocietyVol. 40(8)
Eastern Institute of Technology (NZ), Torrens University Australia (AU)
Reduced inequalities
Openalex Percentile: Top 1%
Artificial Intelligence in Healthcare and Education
12.43
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Can generative AI reliably synthesise literature? exploring hallucination issues in ChatGPT — Noor Haitham Saleem, Amr Adel · AI & Society (2025) | TGRS Research Map | TGRS