Five-year safety and growth response of long-acting PEGylated recombinant human growth hormone in children with growth hormone deficiency—data from CGLS database

• Data from the CGLS database confirms that PEG-rhGh has an acceptable safety profile over five years, with significant improvement in height. Importantly, the data indicate that initiating the treatment earlier yields better outcomes.

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Publication Details

Journal
European Journal of Pediatrics
Published
2025-06-21
DOI
https://doi.org/10.1007/s00431-025-06268-5
Citations
2
Primary Topic
Growth Hormone and Insulin-like Growth Factors
Type
article
Field-Weighted Citation Impact
2.59

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article

Five-year safety and growth response of long-acting PEGylated recombinant human growth hormone in children with growth hormone deficiency—data from CGLS database

Hongxiao Zhang, Wei Gu, Feihong Luo, Xiaoping Luo et al.
2 citations
European Journal of Pediatrics
Growth Hormone and Insulin-like Growth Factors
2.59
article

Five-year safety and growth response of long-acting PEGylated recombinant human growth hormone in children with growth hormone deficiency—data from CGLS database

Hongxiao Zhang, Wei Gu, Feihong Luo, Xiaoping Luo, Yaping Ma, Xiaoyan Huang, Naijun Wan, Hongwei Du, Guimei Li, Chunxiu Gong, Kundi Wang, Yun-Pu Cui, Lirong Ying, Jingsi Luo, Xu Xu, Nan Li, Haiying Wu, Zheng Liu, Zhihong Chen, Yuwen Li, Chunlin Wang, Yuan Li, Huiwen Zhang, Liyan Ma, Haiyan Wei, Yufang Zhao, Rongxiu Zheng, Min Zhu, Liyang Liang, Ruimin Chen, Jin Cai, Yan Zhong, Kan Ye, Wei Wu, Yuqing Chen, Tingting Wang
article en
2 citations

Abstract

• Data from the CGLS database confirms that PEG-rhGh has an acceptable safety profile over five years, with significant improvement in height. Importantly, the data indicate that initiating the treatment earlier yields better outcomes.

European Journal of PediatricsVol. 184(7)
Qingdao University (CN), Jiangnan University (CN), Shandong University (CN), Sun Yat-sen University (CN), Capital Medical University (CN), Jilin University (CN), Nantong University (CN), Peking University (CN), China-Japan Friendship Hospital (CN), XinHua Hospital (CN), Tianjin Medical University General Hospital (CN), Beijing Jishuitan Hospital (CN), Affiliated Hospital of Nantong University (CN), First People's Hospital of Yunnan Province (CN), Sun Yat-sen Memorial Hospital (CN), Changchun Institute of Biological Products (CN), Wuxi Fourth People's Hospital (CN), Suzhou Municipal Hospital (CN), Shandong Provincial Hospital (CN), Affiliated Hospital of Qingdao University (CN), Jinhua Academy of Agricultural Sciences (CN), Lanzhou University Second Hospital (CN), First Hospital of Jilin University (CN), Ningxia Medical University (CN), Hunan Children's Hospital (CN), Ningxia Medical University General Hospital (CN), Peking University Third Hospital (CN), Beijing Children’s Hospital (CN), Jiangsu Province Hospital (CN), Children's Hospital of Fudan University (CN), Tongji Hospital (CN), Jinhua Central Hospital (CN), First Affiliated Hospital Zhejiang University (CN), Huazhong University of Science and Technology (CN), Lanzhou University (CN), Nanjing Medical University (CN)
Huazhong University of Science and Technology, Tongji University, National Key Research and Development Program of China, Tongji Medical College, Huazhong University of Science and Technology
Zero hunger
Openalex Percentile: Top 10%
Growth Hormone and Insulin-like Growth Factors
2.59
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