Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma
Our findings provide novel insights into the molecular mechanisms underlying CA and highlight the diagnostic potential of BAX, BECN1, MAVS, and BCL2 as biomarkers. Targeting PRDEGs may offer new therapeutic avenues, and further research is warranted to validate these findings and explore the clinical applicability of suggested biomarkers in precision medicine for managing CA.
Authors
- Jiao Wei (ORCID: https://orcid.org/0009-0006-1450-7584)
- Xueling Huang
- Ching‐Hsiung Lin (ORCID: https://orcid.org/0000-0001-9407-8578)
- Ke Lian (ORCID: https://orcid.org/0000-0001-9565-8486)
- Di Lian
- Qiuyu Tang
- Meiling Xie
Institutions
- Fujian Medical University (CN)
- Fujian Women and Children Hospital (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-06-20
- DOI
- https://doi.org/10.3389/fgene.2025.1557709
- Citations
- 1
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Fujian Medical University