Integrated transcriptomic, proteomic, and metabolomic analysis unveils key roles of protein and nucleic acid interactions in diabetic ulcer pathogenesis
Our findings identified critical molecular signatures associated with DFUs and lay the groundwork for developing innovative therapeutic strategies to improve clinical outcomes in patients with this challenging condition.
Authors
- Hairui Gao
- Yunfei Gu (ORCID: https://orcid.org/0000-0002-8280-5501)
- Yixin Zhang (ORCID: https://orcid.org/0000-0003-2868-4339)
- Yongpan Lu
- Zhiyu Chen (ORCID: https://orcid.org/0000-0002-9707-3390)
- Xiaomei Sun
- Han Xu (ORCID: https://orcid.org/0009-0007-0468-6336)
- Sen Wang (ORCID: https://orcid.org/0000-0002-0593-2902)
Institutions
- Qingdao University (CN)
- Nanjing University of Chinese Medicine (CN)
- Sun Yat-sen University (CN)
- Beijing Tian Tan Hospital (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Qilu Hospital of Shandong University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-06-20
- DOI
- https://doi.org/10.3389/fendo.2025.1574858
- Citations
- 4
- Primary Topic
- Diabetic Foot Ulcer Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 5.18
Funders
- National Natural Science Foundation of China