Immune profiling of pediatric germ cell tumors identifies key cell populations and novel therapeutic targets
Overall, this study provides new insights into pediatric GCT immunology, supporting the potential for tailored immunotherapeutic strategies targeting the distinct immune profiles of pediatric GCT histologies.
Authors
- Daniel Antunes Moreno (ORCID: https://orcid.org/0000-0002-0764-447X)
- Thaíssa Maria Veiga Faria
- Mariana Tomazini Pinto (ORCID: https://orcid.org/0000-0002-5176-7776)
- Bruna Minniti Mançano (ORCID: https://orcid.org/0000-0001-7489-4906)
- Rui Manuel Reis (ORCID: https://orcid.org/0000-0002-9639-7940)
- Luiz Fernando Lopes (ORCID: https://orcid.org/0000-0001-9737-9245)
- Gisele Eiras Martins
- Ingridy Izabella Vieira Cardoso
- Mabel Cruz (ORCID: https://orcid.org/0009-0006-1408-0840)
- Lenilson Silva
Institutions
- Hospital de Câncer de Barretos (BR)
- University of Minho (PT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-20
- DOI
- https://doi.org/10.3389/fimmu.2025.1579948
- Citations
- 1
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01