Sex differences in ischemic heart disease and evidence gathering related to exposure risk, prevention, and treatment of per- and poly-fluoroalkyl substances
Men with IHD have significantly worse survival rates than women, yet women are more susceptible to PFOA and PFOS toxicity. This study also identifies several PFAS receptor genes that affect key pathways in IHD pathogenesis, which are promising potential targets for future prevention and treatment of PFAS-associated IHD.
Authors
- Hao Tian (ORCID: https://orcid.org/0000-0002-5022-0242)
- Xiaofei Huang (ORCID: https://orcid.org/0000-0002-2429-0546)
Institutions
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Jiangxi Provincial People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-06-20
- DOI
- https://doi.org/10.3389/fpubh.2025.1596125
- Primary Topic
- Per- and polyfluoroalkyl substances research
- Type
- article
- Field-Weighted Citation Impact
- 0.00