Evaluation of a novel Aspergillus IgG lateral flow assay for the diagnosis of non-neutropenic patients with acute and subacute invasive aspergillosis
Compared to the <i>Aspergillus</i> IgG ELISA, the <i>Aspergillus</i> IgG LFA exhibits comparable or superior diagnostic efficiency in IA patients, while offering a faster and more convenient option for clinical diagnosis. The "any-positive" strategy of combined diagnosis with <i>Aspergillus</i> IgG LFA serves as a valuable supplement to current diagnostic approaches, particularly benefiting patients who cannot tolerate invasive bronchoscopic procedures.
Authors
- Jiamei Wang (ORCID: https://orcid.org/0000-0003-3724-0561)
- Xiaomin Cai (ORCID: https://orcid.org/0000-0003-0450-4233)
- Chao Sun (ORCID: https://orcid.org/0000-0002-0577-0130)
- Jinjin Zhong (ORCID: https://orcid.org/0000-0003-2651-5670)
- Yajie Lu (ORCID: https://orcid.org/0000-0003-4554-598X)
- Yuanyuan Li (ORCID: https://orcid.org/0000-0002-9143-8029)
- Huanhuan Zhong
- Y. Cai (ORCID: https://orcid.org/0000-0003-4946-153X)
- Xin Su (ORCID: https://orcid.org/0000-0002-3910-9156)
- Yujie Wang (ORCID: https://orcid.org/0009-0009-6010-2571)
Institutions
- Soochow University (CN)
- Nanjing Drum Tower Hospital (CN)
- Second Affiliated Hospital of Soochow University (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-06-20
- DOI
- https://doi.org/10.3389/fcimb.2025.1599425
- Citations
- 2
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- National Natural Science Foundation of China
- National Science and Technology Major Project
- Nanjing Drum Tower Hospital