Determinants of functional cure in interferon-treated chronic hepatitis B: a retrospective cohort analysis of HBsAg dynamics and clinical predictors
Early HBsAg decline is critical for functional cure. Female patients, HBeAg-negative status, and baseline HBsAg <100 IU/mL predict higher success rates.
Authors
- Jiangyu Liu
- Daqiong Zhou (ORCID: https://orcid.org/0009-0008-4266-8152)
- Feng Zhao (ORCID: https://orcid.org/0000-0003-2410-435X)
- Jianru Jia
- Zichen Zhang (ORCID: https://orcid.org/0000-0002-8919-6243)
- Zhenhuan Cao (ORCID: https://orcid.org/0000-0002-6522-0093)
Institutions
- Capital Medical University (CN)
- Beijing YouAn Hospital (CN)
- Hebei Mental Health Center (CN)
- Baoding People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-06-20
- DOI
- https://doi.org/10.3389/fcimb.2025.1615327
- Citations
- 2
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Beijing Municipal Administration of Hospitals