Three-Year Outcomes of a Bioabsorbable-Polymer Sirolimus-Eluting Stent in Patients With Acute Coronary Syndrome in Korea
Background:The Ultimaster stent (Terumo Corporation), a bioabsorbable polymer sirolimus-eluting stent, has shown promising outcomes across various patient populations; however, long-term efficacy and safety data in patients with acute coronary syndrome (ACS) remain limited.This study evaluated 3-year clinical outcomes in patients with ACS who underwent implantation of the Ultimaster stent, addressing the existing gap in real-world information regarding the applicability and effectiveness of this stent platform.Methods: This multicenter, prospective, observational study was conducted at 13 high-volume cardiovascular centers in South Korea.Data from 923 patients with ACS who received the Ultimaster stent were analyzed.The primary outcomes were major adverse cardiac events (MACE), including all-cause death, nonfatal myocardial infarction (NFMI), and target-vessel revascularization (TVR), evaluated over a 36-month clinical follow-up period.Results: After a median follow-up duration of 1,095 days, the cumulative incidence rates were 10.2% for MACE, 2.3% for all-cause death, 3.4% for NFMI, and 7.4% for TVR.Stent thrombosis occurred in 0.5% of patients.Female sex, prior percutaneous coronary
Authors
- Jei Keon Chae (ORCID: https://orcid.org/0000-0001-5783-7950)
- Jang Hyun Cho (ORCID: https://orcid.org/0000-0002-3792-0017)
- Seok Oh (ORCID: https://orcid.org/0000-0002-6193-2982)
- Seung Uk Lee (ORCID: https://orcid.org/0000-0002-2492-1096)
- Ung Kim (ORCID: https://orcid.org/0000-0002-6009-1843)
- Yongwhan Lim (ORCID: https://orcid.org/0000-0002-2405-1676)
- Doo Sun Sim (ORCID: https://orcid.org/0000-0003-4162-7902)
- Ju Han Kim (ORCID: https://orcid.org/0000-0002-3186-0770)
- Dae Young Hyun (ORCID: https://orcid.org/0000-0002-0038-0125)
- Woong Chol Kang (ORCID: https://orcid.org/0000-0003-4590-7178)
- Kyung‐Kuk Hwang (ORCID: https://orcid.org/0000-0003-3464-3023)
- Joon Ho Ahn (ORCID: https://orcid.org/0000-0003-3465-6596)
- Moo Hyun Kim (ORCID: https://orcid.org/0000-0003-3468-6453)
- Youngkeun Ahn (ORCID: https://orcid.org/0000-0003-2022-9366)
- Hun Sik Park (ORCID: https://orcid.org/0000-0001-7138-1494)
- Keun Ho Park (ORCID: https://orcid.org/0000-0002-2303-4954)
- Jae‐Hwan Lee (ORCID: https://orcid.org/0000-0002-6561-7760)
- Seung Hun Lee (ORCID: https://orcid.org/0000-0002-2337-7826)
- Sang‐Wook Kim (ORCID: https://orcid.org/0000-0002-7208-8596)
- Min Chul Kim (ORCID: https://orcid.org/0000-0001-6026-1702)
- Myung Ho Jeong (ORCID: https://orcid.org/0000-0003-2424-810X)
- Kyung Hoon Cho (ORCID: https://orcid.org/0000-0002-0377-6352)
- Young Joon Hong (ORCID: https://orcid.org/0000-0003-0192-8161)
- Sun Ho Hwang (ORCID: https://orcid.org/0000-0001-5614-6349)
- S.-Y. Kim (ORCID: https://orcid.org/0000-0002-8466-7501)
Institutions
- Dong-A University Hospital (KR)
- Kyungpook National University Hospital (KR)
- Kwangju Christian Hospital (KR)
- Gachon University Gil Medical Center (KR)
- Chonnam National University Hospital (KR)
- Veterans Health Service Medical Center (KR)
- Chosun University Hospital (KR)
- Sungae Hospital (KR)
- Gwangmyeong Mental Health Welfare Center (KR)
- Jeonbuk National University Hospital (KR)
- Chungnam National University Hospital (KR)
- Yeungnam University Medical Center (KR)
- Chung-Ang University Hospital (KR)
- Chungbuk National University Hospital (KR)
- Jeju National University Hospital (KR)
Publication Details
- Journal
- Journal of Cardiovascular Intervention
- Published
- 2025-01-01
- DOI
- https://doi.org/10.54912/jci.2025.0015
- Citations
- 1
- Primary Topic
- Coronary Interventions and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Ministry of Health and Welfare
- Ministry for Food, Agriculture, Forestry and Fisheries
- Centers for Disease Control and Prevention
- Korea Centers for Disease Control and Prevention