Sentinel-Site-Based Surveillance of Mycobacterium tuberculosis Drug Resistance and Epidemiology in Sichuan, China
Our findings prove that WGS is a promising tool for predicting drug resistance to isoniazid, rifampicin, ethambutol, moxifloxacin and levofloxacin in Sichuan. The higher resistance rate to isoniazid emphasizes the urgent need for susceptibility testing surveillance and application management. Improving the diagnosis, treatment and management of patients ≤ 24 years old may reduce the transmission of MTB in Sichuan.
Authors
- Bing Tian Zhao (ORCID: https://orcid.org/0000-0001-9891-3569)
- Yang Zhou (ORCID: https://orcid.org/0000-0003-3072-271X)
- Xichao Ou (ORCID: https://orcid.org/0000-0002-3126-4450)
- Yanlin Zhao (ORCID: https://orcid.org/0000-0002-7890-4312)
- Yuanyuan Song (ORCID: https://orcid.org/0000-0003-1354-8510)
- Chunfa Liu (ORCID: https://orcid.org/0000-0002-4510-8643)
- Ruida Xing (ORCID: https://orcid.org/0000-0001-9696-0214)
- Hui Xia
- Huiwen Zheng (ORCID: https://orcid.org/0000-0003-2194-9963)
- Yi‐Ting Wang (ORCID: https://orcid.org/0000-0003-2008-4435)
- Yang Zheng (ORCID: https://orcid.org/0000-0003-4259-1542)
Institutions
- Capital Medical University (CN)
- Chinese Center For Disease Control and Prevention (CN)
- Beijing University of Agriculture (CN)
- Beijing Children’s Hospital (CN)
- Beijing Center for Disease Prevention and Control (CN)
Publication Details
- Journal
- Antibiotics
- Published
- 2025-06-20
- DOI
- https://doi.org/10.3390/antibiotics14070625
- Citations
- 1
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Natural Science Foundation of Beijing Municipality
- National Key Research and Development Program of China