Aktivitas Ekstrak Daun Jarak Pagar (Jatropha curcas L.) terhadap Pertumbuhan Bakteri Salmonella typhimurium dan Staphylococcus aureus

<p><strong>Most infectious diseases occur in the digestive tract caused by <em>Salmonella typhimurium</em>, while in the respiratory tract caused by <em>Staphylococcus aureus</em>. Continuous use of antibiotics as a treatment for bacterial diseases can result in resistance, therefore it needs to be balanced with the discovery of herbal medicines. <em>Jatropha curcas</em> is thought to have the ability to inhibit the growth of gram-positive and gram-negative bacteria. The purpose of this study was to obtain data and information on the antibacterial activity of <em>Jatropha curcas</em> leaf extract. This study used the paper disc diffusion method with 6 treatments and 3 repetitions. The treatments used were positive control (chloramphenicol), negative control (DMSO), and concentration of <em>Jatropha curcas</em> leaf extract of 10%; 20%; 40% and 80%. The results showed that <em>Jatropha curcas</em> leaf extract at concentrations of 10%, 20%, 40% and 80% had an effect on the growth of <em>Salmonella typhimurium</em> with the average inhibition zone obtained being 9.78; 9.19; 11.95; and 16.88 mm. At concentrations of 10%, 20%, 40% and 80%, it has an effect on the growth of <em>Staphylococcus aureus</em> with the average inhibition zone results obtained being 13.23; 14.83; 16.01; and 18.03 mm.</strong></p><p><strong><em>Keywords</em></strong> <em>– </em><em>Jatropha Leaf Extract, Salmonella Typhimurium, Staphylococcus Aureus.</em></p>