The Landscape of lower respiratory tract herpesviruses in severe pneumonia patients: a multicenter, retrospective study with prospective validation
Herpesviruses are frequently detected in the lower respiratory tract of patients with severe pneumonia, with distinct clinical features across virus types. Co-detection of HSV-1 and CMV was associated with increased 28-day mortality.
Authors
- Yinghe Xu (ORCID: https://orcid.org/0000-0001-8863-7505)
- Chao Xie (ORCID: https://orcid.org/0000-0001-6197-2506)
- Bin Yang (ORCID: https://orcid.org/0000-0003-4105-9263)
- Xiaohan Huang (ORCID: https://orcid.org/0009-0006-5336-4985)
- Lingtong Huang (ORCID: https://orcid.org/0000-0002-2015-6729)
- Hua Zhou (ORCID: https://orcid.org/0000-0001-6508-7942)
- Muhua Dai
- Jin‐Fu Xu (ORCID: https://orcid.org/0000-0002-8039-8973)
- KangChen Li
- Kankai Tang
- Yujie Pan (ORCID: https://orcid.org/0000-0001-7922-9593)
- Hongliu Cai (ORCID: https://orcid.org/0000-0003-3783-8328)
- Laurent Papazian (ORCID: https://orcid.org/0000-0002-8125-9406)
- Lin Zhong (ORCID: https://orcid.org/0000-0002-1822-6919)
- Qiong Chen (ORCID: https://orcid.org/0000-0002-2534-8834)
- Hongyu Wang (ORCID: https://orcid.org/0000-0001-7334-9439)
- Huanzhang Shao (ORCID: https://orcid.org/0009-0008-7344-1807)
- Yiqi Zhuang
- Xuwei He
- Fengqi Liu (ORCID: https://orcid.org/0000-0002-7504-2243)
- Nan Wang (ORCID: https://orcid.org/0000-0002-6576-6096)
- Mingqiang Wang (ORCID: https://orcid.org/0000-0002-7697-0308)
- Peng Shen (ORCID: https://orcid.org/0000-0003-0872-8672)
- Gensheng Zhang (ORCID: https://orcid.org/0000-0001-9298-3961)
- Chao Jiang (ORCID: https://orcid.org/0000-0002-8801-8576)
- Qianqian Wang (ORCID: https://orcid.org/0000-0002-1844-9899)
- Lihong Chu
- Yonghui Xiong
Institutions
- Wenzhou Medical University (CN)
- Huzhou Normal University (CN)
- Zhengzhou University (CN)
- Tongde Hospital of Zhejiang Province (CN)
- Wenzhou Central Hospital (CN)
- Vision Medicals (China) (CN)
- Second Affiliated Hospital of Zhengzhou University (CN)
- Fifth Affiliated Hospital of Zhengzhou University (CN)
- Wuhu No 1 People's Hospital (CN)
- Lishui City People's Hospital (CN)
- Henan Provincial People's Hospital (CN)
- Centre d'Études et de Recherches sur les Qualifications (FR)
- First Hospital of Jiaxing (CN)
- Third People's Hospital of Huzhou (CN)
- Zhengzhou People's Hospital (CN)
- First Affiliated Hospital of Henan University (CN)
- Zhejiang Taizhou Hospital (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
- Taizhou University (CN)
Publication Details
- Journal
- Critical Care
- Published
- 2025-06-20
- DOI
- https://doi.org/10.1186/s13054-025-05496-3
- Citations
- 13
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 17.60
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province