Coil for Microscale Imaging

The aim of this work was to design a coil for magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) to analyze the morphology of cells in vitro. This newly developed hardware, due to compatibility to the 1.5-Tesla MRI scanner (GE Healthcare, Boston, MA, USA), allows for the characterization of cell cultures in vitro. To adapt a designed coil on the 1.5-Tesla MRI scanner, some changes in hardware and software were carried out. The advantage of the designed receiving circuit is the ability to perform MRI with a resolution of 80 μm × 80 μm pixel size. Additionally, this coil can be used to visualize cell cultures and tissue sections, which, due to their small dimensions, could not be imaged on standard MRS and MRI coils at 1.5 Tesla.