Understanding the treatment of acute pancreatitis and its complications -a database for assessing traditional Chinese medicine use
The current version of the TCMAP includes: (i) documentation of 200 evidence-based TCM formulations, with comprehensive details on clinical applications, targets related to AP, and target pathway enrichment analysis, including 449 herbs; (ii) records of 58 natural metabolites, involving extensive information on their potential targets and pharmacological properties; and (iii) integration with a web server enables users to conduct similarity and enrichment analyses of input prescriptions based on herbs, metabolites, and genes. Furthermore, TCMAP also supports discovering anti-AP herb pairs with similar metabolites and targets. Network analysis further provides users with the intrinsic properties of anti-AP formulations. The TCMAP provides a robust data platform for predicting new metabolites and exploring the potential mechanisms of TCM in treating AP. The TCMAP is accessible at https://cellknowledge.com.cn/tcmap.
Authors
- Yu Yang (ORCID: https://orcid.org/0009-0006-1989-7526)
- Jian‐Qin Liu (ORCID: https://orcid.org/0000-0001-9676-8767)
- Yang Zhang (ORCID: https://orcid.org/0000-0002-1317-120X)
- Yali Liu (ORCID: https://orcid.org/0009-0004-6216-0875)
- Zhi Li (ORCID: https://orcid.org/0000-0001-7338-6563)
- W. Hao (ORCID: https://orcid.org/0000-0002-8858-8827)
- Xin Zhou (ORCID: https://orcid.org/0009-0001-9321-3632)
- Xiaofang Ao
Institutions
- North Sichuan Medical University (CN)
- Southwest Medical University (CN)
- Neusoft (China) (CN)
- Sichuan Academy of Traditional Chinese Medicine (CN)
- Chengdu Neusoft University
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-20
- DOI
- https://doi.org/10.3389/fphar.2025.1583040
- Primary Topic
- Lipid metabolism and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Southwest Medical University
- Sichuan Provincial Administration of Traditional Chinese Medicine