Understanding the treatment of acute pancreatitis and its complications -a database for assessing traditional Chinese medicine use

The current version of the TCMAP includes: (i) documentation of 200 evidence-based TCM formulations, with comprehensive details on clinical applications, targets related to AP, and target pathway enrichment analysis, including 449 herbs; (ii) records of 58 natural metabolites, involving extensive information on their potential targets and pharmacological properties; and (iii) integration with a web server enables users to conduct similarity and enrichment analyses of input prescriptions based on herbs, metabolites, and genes. Furthermore, TCMAP also supports discovering anti-AP herb pairs with similar metabolites and targets. Network analysis further provides users with the intrinsic properties of anti-AP formulations. The TCMAP provides a robust data platform for predicting new metabolites and exploring the potential mechanisms of TCM in treating AP. The TCMAP is accessible at https://cellknowledge.com.cn/tcmap.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-06-20
DOI
https://doi.org/10.3389/fphar.2025.1583040
Primary Topic
Lipid metabolism and disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Understanding the treatment of acute pancreatitis and its complications -a database for assessing traditional Chinese medicine use

Yu Yang, Jian‐Qin Liu, Yang Zhang, Yali Liu et al.
Frontiers in Pharmacology
Lipid metabolism and disorders
article

Understanding the treatment of acute pancreatitis and its complications -a database for assessing traditional Chinese medicine use

Yu Yang, Jian‐Qin Liu, Yang Zhang, Yali Liu, Zhi Li, W. Hao, Xin Zhou, Xiaofang Ao
article en

Abstract

The current version of the TCMAP includes: (i) documentation of 200 evidence-based TCM formulations, with comprehensive details on clinical applications, targets related to AP, and target pathway enrichment analysis, including 449 herbs; (ii) records of 58 natural metabolites, involving extensive information on their potential targets and pharmacological properties; and (iii) integration with a web server enables users to conduct similarity and enrichment analyses of input prescriptions based on herbs, metabolites, and genes. Furthermore, TCMAP also supports discovering anti-AP herb pairs with similar metabolites and targets. Network analysis further provides users with the intrinsic properties of anti-AP formulations. The TCMAP provides a robust data platform for predicting new metabolites and exploring the potential mechanisms of TCM in treating AP. The TCMAP is accessible at https://cellknowledge.com.cn/tcmap.

Frontiers in PharmacologyVol. 16
North Sichuan Medical University (CN), Southwest Medical University (CN), Neusoft (China) (CN), Sichuan Academy of Traditional Chinese Medicine (CN), Chengdu Neusoft University, Chengdu University of Traditional Chinese Medicine (CN)
National Natural Science Foundation of China, Southwest Medical University, Sichuan Provincial Administration of Traditional Chinese Medicine
Good health and well-being
Openalex Percentile: Top 75%
Lipid metabolism and disorders
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Understanding the treatment of acute pancreatitis and its complications -a database for assessing traditional Chinese medicine use — Yu Yang, Jian‐Qin Liu, et al. · Frontiers in Pharmacology (2025) | TGRS Research Map | TGRS