Outcomes of Matched Sibling and Haploidentical Donors Hematopoietic Stem Cell Transplantation for Pediatric Severe Aplastic Anemia: A Retrospective Multicenter Study

Pediatric SAA patients undergoing MSD-HSCT had better survival outcomes and less incidence of aGVHD compared to haplo-HSCT. Haplo-HSCT with modified Baltimore conditioning offers a viable alternative, particularly when an MSD is unavailable. Prospective studies are needed to confirm these findings.

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Publication Details

Journal
Hematology/Oncology and Stem Cell Therapy
Published
2025-04-01
DOI
https://doi.org/10.4103/hemoncstem.hemoncstem-d-24-00037
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
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article

Outcomes of Matched Sibling and Haploidentical Donors Hematopoietic Stem Cell Transplantation for Pediatric Severe Aplastic Anemia: A Retrospective Multicenter Study

Diego Medina, Ángela Trujillo, Estefanía Beltrán, Natalia Builes et al.
Hematology/Oncology and Stem Cell Therapy
Hematopoietic Stem Cell Transplantation
article

Outcomes of Matched Sibling and Haploidentical Donors Hematopoietic Stem Cell Transplantation for Pediatric Severe Aplastic Anemia: A Retrospective Multicenter Study

Diego Medina, Ángela Trujillo, Estefanía Beltrán, Natalia Builes, Alexis A. Franco, L. Quiroga, Eliana Manzi, Andrés Felipe Escobar González, Ángela Devia, Mauricio Chaparro, Marcela Estupiñán, Diana Muñoz-Caluce
article en

Abstract

Pediatric SAA patients undergoing MSD-HSCT had better survival outcomes and less incidence of aGVHD compared to haplo-HSCT. Haplo-HSCT with modified Baltimore conditioning offers a viable alternative, particularly when an MSD is unavailable. Prospective studies are needed to confirm these findings.

Hematology/Oncology and Stem Cell TherapyVol. 18(2)
Instituto de Cancerología Las Américas (CO), Fundación Valle del Lili (CO), Hospital Pablo Tobon Uribe (CO)
Good health and well-being
Openalex Percentile: Top 82%
Hematopoietic Stem Cell Transplantation
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