Assessment of Brain Volume and Cortical Thickness in People with HIV and Major Depressive Disorder

Depression in PWH is associated with structural brain changes, particularly in frontal and occipital regions. Although causality cannot be inferred due to the cross-sectional design, these results may enhance our understanding of the neuropathological mechanisms underlying depression in PWH. The findings should be interpreted with caution, given the relatively small sample size and the exclusion of female participants.

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Publication Details

Journal
Current HIV Research
Published
2025-06-20
DOI
https://doi.org/10.2174/011570162x378166250605034405
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessment of Brain Volume and Cortical Thickness in People with HIV and Major Depressive Disorder

Birce Begüm Burhanoğlu, Sabri Atalay, Kadir Aşçıbaşı, Hazal Albayrak Uçak
Current HIV Research
HIV-related health complications and treatments
article

Assessment of Brain Volume and Cortical Thickness in People with HIV and Major Depressive Disorder

Birce Begüm Burhanoğlu, Sabri Atalay, Kadir Aşçıbaşı, Hazal Albayrak Uçak
article en

Abstract

Depression in PWH is associated with structural brain changes, particularly in frontal and occipital regions. Although causality cannot be inferred due to the cross-sectional design, these results may enhance our understanding of the neuropathological mechanisms underlying depression in PWH. The findings should be interpreted with caution, given the relatively small sample size and the exclusion of female participants.

Current HIV ResearchVol. 23(4)
Izmir Kâtip Çelebi University (TR), Abbott (United Kingdom) (GB), Ege University (TR), Sağlık Bilimleri Üniversitesi (TR), Universidad CES (CO), AbbVie (United Kingdom) (GB)
Openalex Percentile: Top 77%
HIV-related health complications and treatments
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