Formulation, Optimization and Design of Capecitabine Nanosuspension to Enhance the Anti-Gastric Cancer Efficacy using Box-Behnken Quality-based Design Study
Developed capecitabine nanosuspension demonstrated better efficacy and effectiveness against gastric cancer, with independent variables like pullulan and poloxamer F207 concentration, along with sonication time, influencing particle size, entrapment efficiency, and drug release.
Authors
- Mayank Kumar Khede (ORCID: https://orcid.org/0000-0002-7149-2378)
- Harekrishna Roy (ORCID: https://orcid.org/0000-0001-7211-2528)
- Sisir Nandi (ORCID: https://orcid.org/0000-0002-9960-6584)
- Bhabani Shankar Nayak (ORCID: https://orcid.org/0000-0002-7664-9645)
Institutions
- Indian Institute of Management Kashipur (IN)
- Sri Sri University (IN)
- Biju Patnaik University of Technology (IN)
- University of Pharmacy Mandalay (MM)
- KIIT University (IN)
- Central Rice Research Institute (IN)
Publication Details
- Journal
- Current Drug Discovery Technologies
- Published
- 2025-06-20
- DOI
- https://doi.org/10.2174/0115701638371974250606041312
- Primary Topic
- Cancer Treatment and Pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 0.00