Brain Targeting Using Nanocolloids for the Management of MultipleSclerosis

Multiple sclerosis (MS) causes sensory and motor deficiencies by breaking the myelin sheath, which inhibits electrical impulses from reaching affected neurons. The blood-brain barrier (BBB) and unanticipated side effects from inadequate targeting are major hurdles to MS treatment. Nanomedicines are being used to deliver therapeutic chemicals to lesions in order to address the limitations of existing MS therapy approaches. Nano-based therapies with deep BBB penetration and selective targeting have shown promising results, emerging as a possible therapy strategy for MS with improved therapeutic effects. This review will suggest the latest developments in nano-colloidsbased therapy for treating MS by evaluating their advantages and disadvantages.

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Publication Details

Journal
Current Drug Delivery
Published
2025-06-18
DOI
https://doi.org/10.2174/0115672018330624241125060045
Primary Topic
RNA Interference and Gene Delivery
Type
article
Field-Weighted Citation Impact
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article

Brain Targeting Using Nanocolloids for the Management of MultipleSclerosis

Kaisar Raza, Smita Jain
Current Drug Delivery
RNA Interference and Gene Delivery
article

Brain Targeting Using Nanocolloids for the Management of MultipleSclerosis

Kaisar Raza, Smita Jain
article en

Abstract

Multiple sclerosis (MS) causes sensory and motor deficiencies by breaking the myelin sheath, which inhibits electrical impulses from reaching affected neurons. The blood-brain barrier (BBB) and unanticipated side effects from inadequate targeting are major hurdles to MS treatment. Nanomedicines are being used to deliver therapeutic chemicals to lesions in order to address the limitations of existing MS therapy approaches. Nano-based therapies with deep BBB penetration and selective targeting have shown promising results, emerging as a possible therapy strategy for MS with improved therapeutic effects. This review will suggest the latest developments in nano-colloidsbased therapy for treating MS by evaluating their advantages and disadvantages.

Current Drug DeliveryVol. 22
Central University of Rajasthan (IN)
Good health and well-being
Openalex Percentile: Top 87%
RNA Interference and Gene Delivery
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