Polygenic score from MODY genes is associated with type 1 diabetes and disease characteristics
Our study suggests that a polygenic approach based on MODY genes may discriminate T1D from HC and may contribute to patient stratification, helping to better understand T1D heterogeneity.
Authors
- Klemen Dovč (ORCID: https://orcid.org/0000-0001-9201-2145)
- Davide Tinti (ORCID: https://orcid.org/0000-0002-7265-9360)
- Ivana Rabbone (ORCID: https://orcid.org/0000-0003-4173-146X)
- Dario Iafusco (ORCID: https://orcid.org/0000-0002-9398-3856)
- Gianluca Tamaro (ORCID: https://orcid.org/0000-0003-1635-9141)
- Tadej Battelino (ORCID: https://orcid.org/0000-0002-0273-4732)
- Stefania Cappellani (ORCID: https://orcid.org/0000-0002-1126-5202)
- Roberto Franceschi (ORCID: https://orcid.org/0000-0002-2230-7148)
- Gianluca Tornese (ORCID: https://orcid.org/0000-0002-4395-3915)
- Angela Zanfardino (ORCID: https://orcid.org/0000-0003-0641-1321)
- Camilla Morosini (ORCID: https://orcid.org/0000-0002-4022-0900)
- Eulalia Catamo (ORCID: https://orcid.org/0000-0002-4701-9134)
- Elena Faleschini (ORCID: https://orcid.org/0000-0002-7045-5524)
- Riccardo Bonfanti (ORCID: https://orcid.org/0000-0002-4104-2763)
- Andrea Conti (ORCID: https://orcid.org/0009-0001-2127-4022)
- Antonietta Robino
- Luana Aldegheri (ORCID: https://orcid.org/0009-0004-9116-2685)
Institutions
- Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
- University of Trieste (IT)
- University of Ljubljana (SI)
- Vita-Salute San Raffaele University (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- IRCCS Materno Infantile Burlo Garofolo (IT)
- Ljubljana University Medical Centre (SI)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Ospedale Santa Chiara (IT)
- IRCCS Ospedale San Raffaele (IT)
Publication Details
- Journal
- Acta Diabetologica
- Published
- 2025-06-20
- DOI
- https://doi.org/10.1007/s00592-025-02544-w
- Citations
- 1
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Ministero della Salute
- Javna Agencija za Raziskovalno Dejavnost RS