L-Selenomethylselenocysteine Exerts Inhibitory Effects on the Progressionof Esophageal Cancer by Targeting the PI3K/AKT Signaling Pathway
L-SeMC has a strong anticancer effect on human esophageal cancer cells and promotes apoptosis by inhibiting the PI3K/AKT signaling pathway, suggesting that L-SeMC may represent a novel strategy for the treatment of esophageal cancer.
Authors
- Cheng-Bao Wang
- Longjie Wang (ORCID: https://orcid.org/0000-0002-8179-0715)
- Ke Ji (ORCID: https://orcid.org/0000-0002-0085-9646)
- Genlin Li (ORCID: https://orcid.org/0000-0001-7524-4999)
- Jiayao Yuan (ORCID: https://orcid.org/0000-0002-5437-8944)
- Shaobu Wang (ORCID: https://orcid.org/0000-0002-3607-3573)
- Hanbing Li (ORCID: https://orcid.org/0000-0003-3873-4061)
- Su Wu (ORCID: https://orcid.org/0000-0002-2278-2993)
- Yu Wang (ORCID: https://orcid.org/0000-0003-4725-0472)
- Linlin Wang (ORCID: https://orcid.org/0000-0001-5747-7705)
Institutions
- Henan University of Traditional Chinese Medicine (CN)
- Henan Tianguan Group (China) (CN)
- Henan Energy & Chemical Industry Group (China) (CN)
- Zhengzhou Central Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Recent Patents on Anti-Cancer Drug Discovery
- Published
- 2025-06-18
- DOI
- https://doi.org/10.2174/0115748928355152250527060605
- Primary Topic
- Selenium in Biological Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.00