N-(2-((2-(1H-indol-3-yl)ethyl)carbamoyl)phenyl)furan-2-carboxamide
In the present study, we describe the synthesis of N-(2-((2-(1H-indol-3-yl)ethyl)carbamoyl)phenyl)furan-2-carboxamide via a two-step reaction sequence. Initially, isatoic anhydride was reacted with tryptamine to afford the corresponding intermediate, which was subsequently subjected to acylation using furan-2-carbonyl chloride. The final product was comprehensively characterized by melting point analysis, 1H and 13C NMR, HSQC, IR, and MS spectrometry. The combined spectroscopic and analytical data unequivocally confirm the successful synthesis and structural integrity of the target compound.
Authors
- Iliyan Ivanov (ORCID: https://orcid.org/0000-0002-4662-3735)
- Diyana Dimitrova (ORCID: https://orcid.org/0009-0009-2623-0043)
- Dimitar G. Bojilov (ORCID: https://orcid.org/0000-0001-6569-8348)
- Stanimir P. Manolov (ORCID: https://orcid.org/0000-0002-0314-6553)
Institutions
- Plovdiv University (BG)
Publication Details
- Journal
- Molbank
- Published
- 2025-06-20
- DOI
- https://doi.org/10.3390/m2025
- Primary Topic
- Synthesis and Biological Evaluation
- Type
- article
- Field-Weighted Citation Impact
- 0.00