Deep Brain Stimulation for <scp> <i>VPS16</i> </scp> ‐Related Dystonia: A Multicenter Study

DBS was an effective treatment for three-quarters of patients with pathogenic VPS16 variants in our cohort. Mean motor improvement was most pronounced at the 1-year FU, but persisted at the last FU despite disease progression. ANN NEUROL 2025;98:711-725.

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Publication Details

Journal
Annals of Neurology
Published
2025-06-20
DOI
https://doi.org/10.1002/ana.27290
Citations
5
Primary Topic
Neurological disorders and treatments
Type
article
Field-Weighted Citation Impact
6.95

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article

Deep Brain Stimulation for VPS16 ‐Related Dystonia: A Multicenter Study

Veronika Jurková, Katja Lohmann, Petra Havránková, Simone Zittel et al.
5 citations
Annals of Neurology
Neurological disorders and treatments
6.95
article

Deep Brain Stimulation for VPS16 ‐Related Dystonia: A Multicenter Study

Veronika Jurková, Katja Lohmann, Petra Havránková, Simone Zittel, Barbara Garavaglia, Manju A. Kurian, Marina A.J. Tijssen, Thomas Foltynie, Kamil Knorovsky, Vladimír Haň, Jens Volkmann, Alberto Mazzoni, Ahmet Kaymak, Veronika Magocova, Patricia Limousin, Claudio Baiata, Ľuboš Ambro, David Murphy, Liesanne M. Centen, Jan Niklas Petry‐Schmelzer, Harith Akram, Robert Jech, Elena Moro, Martje E. van Egmond, Tatiana Svoreňová, Miriam Ostrožovičová, Roberto Eleopra, Luigi Romito, Wolfgang Hamel, Nico Golfrè Andreasi, Steffen Paschen, Michael T. Barbe, Henry Houlden, Michael Zech, Matěj Škorvánek, Ludvic Zrinzo, Alberto Albanese, Chiara Reale, Francesca Magrinelli, Doreen Gruber, Eoin Mulroy, Kirsten E. Zeuner, Vincenzo Levi, Giovanna Zorzi, Laura Cif, Aurelia Kollova
article en
5 citations

Abstract

DBS was an effective treatment for three-quarters of patients with pathogenic VPS16 variants in our cohort. Mean motor improvement was most pronounced at the 1-year FU, but persisted at the last FU despite disease progression. ANN NEUROL 2025;98:711-725.

Annals of NeurologyVol. 98(4)
University Medical Center Groningen (NL), Universität Hamburg (DE), Scuola Superiore Sant'Anna (IT), Queen Mary University of London (GB), University of Groningen (NL), University of Cologne (DE), University of Pavol Jozef Šafárik (SK), Charles University (CZ), University of Würzburg (DE), Great Ormond Street Hospital (GB), Centre Hospitalier Universitaire de Grenoble (FR), Helmholtz Zentrum München (DE), Fondazione Istituto Neurologico Nazionale Casimiro Mondino (IT), University Medical Center Hamburg-Eppendorf (DE), Univerzitná Nemocnica Louisa Pasteura (SK), Hôpital Gui de Chauliac (FR), University Hospital Schleswig-Holstein (DE), Munich Cluster for Systems Neurology (DE), Neurologisches Fachkrankenhaus für Bewegungsstörungen/Parkinson (DE), Institute for Advanced Study (DE), Grenoble Institute of Neurosciences (FR), National Hospital for Neurology and Neurosurgery (GB), University Hospital Cologne (DE), Vitenparken (NO), General University Hospital in Prague (CZ), Fondazione IRCCS Istituto Neurologico Carlo Besta (IT), Bioscience (Slovakia) (SK), University College London (GB), Technical University of Munich (DE), Université Grenoble Alpes (FR), University of Lübeck (DE), University of Lausanne (CH)
Michael J. Fox Foundation for Parkinson's Research, American Parkinson Disease Association, Australian Government, National Institute for Health and Care Research, Parkinson's UK, University College London, European Commission, Deutsche Forschungsgemeinschaft, Bundesministerium für Bildung und Forschung, Else Kröner-Fresenius-Stiftung, Ministero della Salute, Fondazione Pierfranco e Luisa Mariani, Agentúra na Podporu Výskumu a Vývoja, Technische Universität München, UCLH Biomedical Research Centre, Institute for Advanced Study, Technische Universität München
Openalex Percentile: Top 3%
Neurological disorders and treatments
6.95
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