Membranous Nephropathy and Papillary Thyroid Cancer: A Case Report
This case report highlights a rare association between membranous nephropathy (MN) and papillary thyroid carcinoma (PTC) in a 66-year-old female with progressive renal dysfunction. Following a confirmed diagnosis of MN with negative phospholipase A2 receptor (PLA2R) staining, imaging revealed a thyroid malignancy, and total thyroidectomy led to clinical improvement, suggesting a paraneoplastic mechanism. This case underscores the importance of oncologic screening in MN patients and the need for further research into the pathophysiological links between MN and thyroid cancer.
Authors
- Ohad Bitan
- Arad Dotan (ORCID: https://orcid.org/0000-0002-3300-3676)
- Galit Avior (ORCID: https://orcid.org/0000-0002-6716-8671)
- David Yogev (ORCID: https://orcid.org/0000-0001-7321-5887)
Institutions
- Tel Aviv University (IL)
- Technion – Israel Institute of Technology (IL)
- Sheba Medical Center (IL)
Publication Details
- Journal
- The Laryngoscope
- Published
- 2025-06-20
- DOI
- https://doi.org/10.1002/lary.32360
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00