CORRELATION OF CENTRAL MACULAR THICKNESS ON OCT FOLLOWING PANRETINAL PHOTOCOAGULATION WITH HBA1C AMONG DIABETIC PATIENTS

Background: PDR is defined as  the formation of  new retinal vessels  due to poor glycemic control  patients with diabetes mellitus .Among the risk factors, one of the most significant risk factor  that predicts this complication is the  long term hyperglycemia with the long  duration of  disease, that ultimately  causes the development of  advance diabetic eye disease .The definite treatment of PDR is via PRP laser  , that reduce oxygen demand of retinal tissue and prevents further ischemic mediated damage. Objective: Find out any change in the CMT and its correlation with HbA1c following PRP by OCT   macula among patients with PDR. Methods: This study was conducted at the department of Ophthalmology, Services Institute of Medical Sciences, Services Hospital Lahore, Pakistan. Study period was of six months from December 2023 to June 2024. This study included a total of fourty eyes from fourty patients with diagnosed proliferative diabetic retinopathy , study participants were divided into two groups, Group mA with HbA1c below 7.5% comprising of  twenty  patients , and group B comprising of twenty  patients with HbA1c between 8.5 and 9.0%, both study  groups  were treated with   pan retinal photocoagulation performed  in single session with 1500 laser  burn spots This laser treatment was followed by Optical coherence tomography , four weeks after the sessions. Central macular thickness was measured for a change before and after PRP laser sessions. Results: In our study, patients had a mean age of  48.71±2.42 years, ,the measured  mean baseline CMT  before the PRP laser sessions was recorded at baseline  thickness  of 230.45±5.0 and four weeks after the PRP session ,the  mean CMT value was  238.50±5.30 among patients in  group A and 257±3.5 microns among group B patients. (p-value of 0.001) Conclusion: There was no statistically proven significant change found in macular thickness   before and after PRP session upto to four weeks of follow-up via OCT macula