The relationship between vitamin D levels and Alzheimer’s disease risk: insights from a centenarian study of Chinese women
Among Chinese female centenarians, serum vitamin D₃ levels are inversely associated with AD risk in a dose-dependent manner, particularly below 29.3 ng/mL. These findings highlight the relevance of vitamin D₃ as a potentially modifiable factor in cognitive aging and support further interventional studies in the oldest-old population.
Authors
- Hongzhou Liu (ORCID: https://orcid.org/0000-0002-9930-4535)
- Jiangbo Liu (ORCID: https://orcid.org/0000-0002-8781-0414)
- Shihui Fu (ORCID: https://orcid.org/0000-0001-6707-9049)
- Xujie Wang (ORCID: https://orcid.org/0000-0001-8638-9878)
- M R Liu
- Dong Song (ORCID: https://orcid.org/0000-0002-6179-1120)
- Yi Mei (ORCID: https://orcid.org/0000-0003-0682-1363)
- Yupeng Li (ORCID: https://orcid.org/0000-0003-0843-7592)
- Fei Wang (ORCID: https://orcid.org/0000-0002-4146-5379)
- Xuhui Liu (ORCID: https://orcid.org/0000-0002-2418-0291)
- Liang Xu
Institutions
- Hebei Medical University (CN)
- Tianjin First Center Hospital (CN)
- Qinghai University Affiliated Hospital (CN)
- Tianjin Infectious Diseases Hospital (CN)
- Aerospace Center Hospital (CN)
- Lanzhou University Second Hospital (CN)
- Hainan 301 Hospital (CN)
- Tianjin Medical University Eye Hospital (CN)
- Chinese People's Liberation Army (CN)
- Tianjin haihe hospital (CN)
- Tianjin Medical University (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-06-20
- DOI
- https://doi.org/10.3389/fnut.2025.1628732
- Citations
- 2
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94