Atypical Presentation of Localised Annular Secondary Syphilis Confined to Genitals

Syphilis, caused by the bacterium Treponema pallidum subspecies Pallidum , is known for its diverse mucocutaneous manifestations, earning it the moniker ‘Great Imitator’ due to its resemblance to various other dermatoses. This case report discusses a rare presentation of localised annular secondary syphilis (SS) confined to the genitals, a presentation that challenges the usual broad-spectrum manifestations of the disease. A 22-year-old male presented with multiple asymptomatic erythematous annular plaques on his scrotum and penis, accompanied by a condyloma lata lesion. The diagnosis was confirmed with serologic tests. This case underscores the importance of considering syphilis in differential diagnoses of atypical cutaneous presentations. Early recognition and treatment are crucial to prevent progression to more severe stages of the disease. This case also highlights the need for heightened awareness of localised presentations of SS, as they are less frequently reported in the literature.