Enhancing drug efficacy through nanoparticle-based delivery systems: a study on targeted cancer therapy
Lipid nanoparticles improve the therapeutic index of doxorubicin by enhancing its bioavailability and reducing off-target toxicity. These findings highlight their potential as an advanced drug delivery system, warranting further preclinical and clinical investigations.
Authors
- Nihal AlMuraikhi (ORCID: https://orcid.org/0000-0003-4996-7565)
- Hajar Alghamdi
- Tarig M.S. Alnour (ORCID: https://orcid.org/0000-0001-5880-793X)
- Salah Alghamdi (ORCID: https://orcid.org/0009-0009-1852-3399)
- Mahmoud A.H. Mostafa (ORCID: https://orcid.org/0000-0002-2117-6588)
- Ahmed Senbel
- Dahlia Mirdad
- Abdulmohsen Alrohaimi (ORCID: https://orcid.org/0000-0001-9107-773X)
Institutions
- Mansoura University (EG)
- Al-Azhar University (EG)
- Shaqra University (SA)
- Taibah University (SA)
- King Saud University (SA)
- Fahd bin Sultan University (SA)
- University of Jeddah (SA)
- University of Hafr Al-Batin (SA)
- University of Bisha (SA)
- University of Tabuk (SA)
- Assiut University (EG)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1097/js9.0000000000002702
- Citations
- 5
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 2.99