Formulation And Evaluation of Chebulinic Acid for Mouth Gargle

Oral infections and dental diseases are commonly associated with microbial biofilms. Chebulinic acid, a tannin from Terminalia chebula, exhibits strong antimicrobial, anti-inflammatory, and antioxidant properties. This study presents the formulation and evaluation of a chebulinic acid-based mouth gargle aimed at improving oral health. The formulation was optimized for solubility, stability, pH, and viscosity to ensure effectiveness and patient compliance. Antimicrobial studies showed significant inhibition of Streptococcus mutans, and stability tests confirmed the formulation’s shelf-life. These findings support chebulinic acid as a natural, effective alternative to conventional mouthwashes, with further clinical studies recommended

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Publication Details

Journal
International Journal For Multidisciplinary Research
Published
2025-06-19
DOI
https://doi.org/10.36948/ijfmr.2025.v07i03.48135
Primary Topic
Phytochemicals and Medicinal Plants
Type
article
Field-Weighted Citation Impact
0.00
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article

Formulation And Evaluation of Chebulinic Acid for Mouth Gargle

K. L. Chaudhary, Rahul Kishore Chaudhari, Bhargav Kawale, Jai Ranglani - et al.
International Journal For Multidisciplinary Research
Phytochemicals and Medicinal Plants
article

Formulation And Evaluation of Chebulinic Acid for Mouth Gargle

K. L. Chaudhary, Rahul Kishore Chaudhari, Bhargav Kawale, Jai Ranglani -, DeepSonchhatra, Suraj Maladhare -
article en

Abstract

Oral infections and dental diseases are commonly associated with microbial biofilms. Chebulinic acid, a tannin from Terminalia chebula, exhibits strong antimicrobial, anti-inflammatory, and antioxidant properties. This study presents the formulation and evaluation of a chebulinic acid-based mouth gargle aimed at improving oral health. The formulation was optimized for solubility, stability, pH, and viscosity to ensure effectiveness and patient compliance. Antimicrobial studies showed significant inhibition of Streptococcus mutans, and stability tests confirmed the formulation’s shelf-life. These findings support chebulinic acid as a natural, effective alternative to conventional mouthwashes, with further clinical studies recommended

International Journal For Multidisciplinary ResearchVol. 7(3)
Openalex Percentile: Top 78%
Phytochemicals and Medicinal Plants
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